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QuickView for CP-10 (gene)


Gene Symbol:
S100A8 Homo sapiens Homo sapiens
Full name:
S100 calcium binding protein A8
Synonyms:
OTTHUMP00000015329, OTTHUMP00000015330, MIF, migration inhibitory factor-related protein 8, MRP-8, P8, MRP8, NIF, CAGA, calgranulin A, calgranulin-A, calprotectin L1L subunit, cystic fibrosis antigen, 60B8AG, CP-10, CFAG, CGLA, MA387, leukocyte L1 complex light chain, L1Ag, S100 calcium binding protein A8, S100 calcium-binding protein A8, S100 calcium-binding protein A8 (calgranulin A), protein S100-A8, urinary stone protein band A
Genomic Location:
Chr 1: 151629132-151630173
Description:
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at leas...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 1
1q21


Transcripts Names
NM_002964



GO Molecular Function

fatty acid binding | icosanoid binding | long-chain fatty acid binding | cation binding | carboxylic acid binding | lipid binding | receptor binding | arachidonic acid binding | Toll-like receptor binding | binding | cytoskeletal protein binding | Toll-like receptor 4 binding | monocarboxylic acid binding | icosatetraenoic acid binding | ion binding | protein binding | zinc ion binding | transition metal ion binding | microtubule binding | calcium ion binding | tubulin binding | metal ion binding | RAGE receptor binding

GO Biological Process

regulation of biological process | regulation of cysteine-type endopeptidase activity | cell motility | response to lipopolysaccharide | positive regulation of apoptotic process | regulation of biosynthetic process | positive regulation of sequence-specific DNA binding transcription factor activity | regulation of programmed cell death | regulation of biological quality | response to metal ion | defense response | cellular chemical homeostasis | regulation of organelle organization | regulation of response to stimulus | cellular process | death | localization | cellular homeostasis | regulation of defense response | sequestering of zinc ion | positive regulation of catalytic activity | regulation of nucleobase-containing compound metabolic process | cellular response to chemical stimulus | response to inorganic substance | regulation of cellular process | positive regulation of cell growth | regulation of apoptotic process | regulation of metabolic process | catabolic process | regulation of response to stress | response to stimulus | defense response to fungus | response to chemical stimulus | neutrophil chemotaxis | positive regulation of peptidase activity | leukocyte aggregation | response to stress | regulation of macromolecule biosynthetic process | regulation of response to external stimulus | positive regulation of cysteine-type endopeptidase activity | programmed cell death | response to alcohol | response to molecule of bacterial origin | maintenance of location | cellular catabolic process | cell chemotaxis | response to ethanol | leukocyte migration | locomotion | apoptotic process | zinc ion homeostasis | cell migration | regulation of peptidase activity | positive regulation of inflammatory response | taxis | regulation of catalytic activity | wound healing | regulation of gene expression | cellular ion homeostasis | regulation of macromolecule metabolic process | regulation of nitrogen compound metabolic process | single-organism process | regulation of cysteine-type endopeptidase activity involved in apoptotic process | multi-organism process | positive regulation of hydrolase activity | biological regulation | regulation of primary metabolic process | cellular component movement | positive regulation of response to external stimulus | positive regulation of endopeptidase activity | cellular zinc ion homeostasis | cation homeostasis | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | positive regulation of biological process | autophagy | regulation of cellular macromolecule biosynthetic process | response to bacterium | response to fungus | cellular cation homeostasis | regulation of cellular metabolic process | induction of programmed cell death | positive regulation of defense response | inflammatory response | leukocyte chemotaxis | defense response to bacterium | homeostatic process | response to zinc ion | regulation of RNA metabolic process | neutrophil aggregation | positive regulation of molecular function | cytokine production | chronic inflammatory response | regulation of growth | response to organic substance | chemokine production | regulation of cellular biosynthetic process | response to wounding | regulation of sequence-specific DNA binding transcription factor activity | leukocyte cell-cell adhesion | metabolic process | activation of cysteine-type endopeptidase activity involved in apoptotic process | regulation of RNA biosynthetic process | chemical homeostasis | positive regulation of cell death | cell adhesion | cellular response to stimulus | regulation of hydrolase activity | induction of apoptosis | cell death | positive regulation of NF-kappaB transcription factor activity | positive regulation of programmed cell death | ion homeostasis | cell-cell adhesion | leukocyte migration involved in inflammatory response | positive regulation of growth | regulation of transcription, DNA-dependent | regulation of molecular function | regulation of endopeptidase activity | positive regulation of response to stimulus | cellular divalent inorganic cation homeostasis | sequestering of metal ion | response to biotic stimulus | response to external stimulus | localization of cell | regulation of cell growth | positive regulation of cellular process | single-multicellular organism process | acute inflammatory response | immune system process | cellular metabolic process | regulation of cell death | regulation of inflammatory response | chemotaxis | biological adhesion | divalent inorganic cation homeostasis | activation of cysteine-type endopeptidase activity | regulation of cellular component organization | homotypic cell-cell adhesion | regulation of cytoskeleton organization | response to other organism | multicellular organismal process

GO Cellular Component

cell | intracellular non-membrane-bounded organelle | cytoplasm | intracellular organelle | plasma membrane | cell part | extracellular region | organelle | extracellular space | cell periphery | extracellular region part | cytoplasmic part | non-membrane-bounded organelle | cytosol | cytoskeleton | intracellular part | intracellular | membrane