Clear Search sequence regions


  • catalysis (1)
  • cefoselis (4)
  • cefozopran (1)
  • cephalosporins (2)
  • liquid (1)
  • mass (2)
  • Sizes of these terms reflect their relevance to your search.

    The process of degradation was studied by using an HPLC-DAD method. Two degradation products were identified with a hybrid ESI-Q-TOF mass spectrometer. The influence of temperature and relative air humidity (RH) on the stability of cefoselis sulfate was investigated. In the solid state at increased RH the degradation of cefoselis sulfate was an autocatalytic reaction of the first order with respect to substrate concentration while in dry air was first-order reaction depending on the substrate concentration. The kinetic and thermodynamic parameters of degradation were calculated. Copyright © 2015 Elsevier B.V. All rights reserved.

    Citation

    Przemysław Zalewski, Robert Skibiński, Alicja Talaczyńska, Magdalena Paczkowska, Piotr Garbacki, Judyta Cielecka-Piontek. Stability studies of cefoselis sulfate in the solid state. Journal of pharmaceutical and biomedical analysis. 2015 Oct 10;114:222-6

    Expand section icon Mesh Tags

    Expand section icon Substances


    PMID: 26073113

    View Full Text